European Network to Cure ALS (ENCALS), Ljubljana 2017
40 Lectures · May 18, 2017
About
Amyotrophic lateral sclerosis (ALS) is a devastating disease that is still lacking an effective cure. In recent year, research advances offer hope that ALS will eventually become a preventable and treatable disease. Patients, researchers and clinicians worldwide have joined forces in various international projects to make progress towards this goal. European Network to Cure ALS (ENCALS) is a network of ALS centres in Europe that supports such collaborations. 2017 is an exciting year for the ALS community since positive clinical drug trials are promising new treatments after more than two decades.
The ENCALS Meeting 2017 was hosted by the Ljubljana ALS Centre and the Slovenian Society of Clinical Neurophysiology. In three days, a series of plenary lectures, thematic sessions and poster resentations brought together international researchers and clinicians to discuss the advances in research and clinical care.
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Uploaded videos:
Opening Session
Opening session
Jul 21, 2017
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826 Views
Keynotes
Protein-RNA complexes & ALS: insights from iCLIP
Jul 21, 2017
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964 Views
Masitinib as an add-on therapy to riluzole is beneficial in the treatment of amy...
Jul 21, 2017
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3069 Views
Invited Talks
Tracking ALS progression using neuroimaging
Jul 21, 2017
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923 Views
The panorama of ALS genomics
Jul 21, 2017
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897 Views
Cognitive and behavioural symptoms in ALS: why are they there and how to assess ...
Jul 21, 2017
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759 Views
Gene expression profiling in ALS: past, present and future
Jul 21, 2017
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866 Views
ENCALS Young Investigator Award 2017
Clinical, pathological and molecular characterisation of C9orf72-ALS leads to id...
Sep 22, 2017
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1158 Views
Session 1: Therapy
Bringing gene therapy based SOD1 silencing towards human trials: A highly effica...
Jul 21, 2017
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759 Views
Intraspinal injection of human mesenchymal stromal cells in SOD1G93A ALS mice
Jul 21, 2017
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940 Views
Session 2: Clinical & Epidemiology
Euro-MOTOR: A multi-centre population-based case-control study of metals and sol...
Jul 21, 2017
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816 Views
Global ALS/MND "big data" collaboration environment in a post-PRO-ACT era
Jul 21, 2017
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898 Views
The time of the ALSFRS-R to decrease to 50% (D50) in a sigmoidal decay model suf...
Jul 21, 2017
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1571 Views
The role of pre-morbid diabetes on developing amyotrophic lateral sclerosis
Jul 21, 2017
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863 Views
AB Science Satellite Meeting
Masitinib for the treatment of amyotrophic lateral sclerosis (ALS): preclinical ...
Jul 21, 2017
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1130 Views
Session 3: Genetics A
Discovery of microRNA gene mutations in ALS patient genomes
Jul 21, 2017
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794 Views
Whole genome sequencing as tool to unravel rare variants associated with ALS sur...
Jul 21, 2017
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775 Views
Serum microRNA-profiles indicate a role of Fragile-X-related proteins for ALS
Jul 21, 2017
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747 Views
The Project MinE data browser: bringing whole-genome sequencing data in ALS to r...
Jul 21, 2017
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817 Views
Session 4: Genetics B
Integrating copy-number analysis with structural-variation detection in 50 ALS p...
Jul 21, 2017
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805 Views
ATXN1: expanding the spectrum of polyglutamine repeats in ALS
Jul 21, 2017
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1384 Views
A high throughput gene, environment and epigenetics database and analysis system...
Jul 21, 2017
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855 Views
MicroRNAs analysis of patient-derived iPSCs as molecular therapy for ALS
Jul 21, 2017
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914 Views
Session 5: Cognition & Imaging
The brief Dimensional Apathy Scale (b-DAS): Mokken analysis and scale reduction
Jul 21, 2017
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1148 Views
Assessing behaviour in ALS: the importance of using disease-specific tools
Jul 21, 2017
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879 Views
Hypothalamic atrophy correlates with onset of disease-defining symptoms in patie...
Jul 21, 2017
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772 Views
A PET/CT approach to spinal cord metabolism
Jul 21, 2017
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883 Views
Session 6: Disease mechanisms A
Role of FUS in post synaptic neuromuscular junction differentiation
Jul 21, 2017
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1084 Views
Developing vertebrate models to highlight the functional relevance of Nefl and m...
Jul 21, 2017
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804 Views
Phase separation of C9orf 72 dipeptide repeats perturbs stress granule dynamics
Jul 21, 2017
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658 Views
Dynamic polymerization of TDP-43 in health and disease
Jul 21, 2017
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940 Views
Session 7: Disease mechanisms B
Deciphering the function and mechanisms of C9ORF72 in ALS
Jul 21, 2017
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864 Views
Live imaging of RNA dynamics for genetic forms of amyotrophic lateral sclerosis ...
Jul 21, 2017
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891 Views
Two G-quadruplex structures adopted by oligonucleotide model of ALS and FTD link...
Jul 21, 2017
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822 Views
The role of valosin containing protein (VCP) in the clearance of toxic misfolded...
Jul 21, 2017
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893 Views
Session 8: Disease mechanisms C
Intranuclear (G4C2)n RNA foci, transcribed from C9ORF72 hexanucleotide expansio...
Jul 21, 2017
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983 Views
C9orf 72 interacts with coilin and influences Cajal body dynamics and splicing
Jul 21, 2017
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992 Views
RNA toxicity in a zebrafish model for C9orf 72 ALS is abrogated by Pur-alpha and...
Jul 21, 2017
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939 Views
Secretion of toxic exosomes by muscle cells of ALS patients: role in ALS pathoge...
Jul 21, 2017
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1120 Views
Closing of the Meeting
Closing of the meeting
Jul 21, 2017
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766 Views