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Developing vertebrate models to highlight the functional relevance of Nefl and miRNAs in ALS pathogenesis
Published on Jul 21, 2017803 Views
A striking number of genes, including TDP-43, FUS and ATXN2 implicated in ALS pathogenesis encode proteins with functions in RNA metabolism. Also, preliminary results suggest that miRNAs are aberr
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Chapter list
Implication of Nefl in the pathogenesis of ALS00:00
ALS : state of the art00:16
NEFL : Neurofilament, light polypeptide01:00
Developing zebrafish models01:52
Nefl in zebrafish : identification02:39
Nefl in zebrafish : role - 103:25
Nefl in zebrafish : role - 204:29
Nefl in zebrafish : role - 305:23
Nefl in zebrafish : role - 406:02
Nefl in zebrafish : role - 506:27
Nefl in zebrafish : role - 607:21
Nefl in zebrafish : role - 707:52
Nefl in zebrafish : role - 808:33
Nefl in zebrafish : role - 908:48
Conclusion/Perspectives09:07
Thank you and…10:01