Lecture 30 - Esomeprazole as an Example of Drug Testing and Usage

author: J. Michael McBride, Department of Chemistry, Yale University
recorded by: Yale University
published: June 10, 2010,   recorded: November 2008,   views: 2964
released under terms of: Creative Commons Attribution No Derivatives (CC-BY-ND)
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Description

The chemical mode of action of omeprazole is expected to be insensitive to its stereochemistry, making clinical trials of the proposed virtues of a chiral switch crucial. Design of the clinical trials is discussed in the context of marketing. Otolaryngologist Dr. Dianne Duffey provides a clinician's perspective on the testing and marketing of pharmaceuticals, on the FDA approval process, on clinical trial system, on off-label uses, and on individual and institutional responsibility for evaluating pharmaceuticals.

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Reading assignments, problem sets, PowerPoint presentations, and other resources for this lecture can be accessed from Professor McBride's on-campus course website, which was developed for his Fall 2008 students. Please see Resources section below.

Resources:

Professor McBride's web resources for CHEM 125 (Fall 2008)

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