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Human Brain Project: implications for neurology
Published on Sep 07, 20152432 Views
We now know that a single human gene mutation may present with any of multiple phenotypes, and vice versa, that a range of genetic abnormalities may cause a single disease phenotype. These observation
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Chapter list
Human Brain Project Implications For Neuroscience00:00
Neuroscience across scales00:54
Motivation 103:43
Nobel contributions to neuroscience05:54
Motivation 207:31
Has phenomenology reached a dead end09:33
Motivation 314:01
What is a flagship of enterprise and technology19:03
Impact of ict24:21
HBP - a neuroinformatics project27:35
Disease space and genetic associations30:15
Informatics integrate data31:06
Functional connections33:12
Structural systems34:13
Structural characterisation35:33
Classification & connections36:52
Informatics refine pattern analyses37:54
Anatomical connectomics39:56
Confronting paradigms41:10
Constructing a blueprint fot the brain45:11
Future medicine50:09
The declining interest of pharma51:59
Data sources and challenges52:33
Ethical challenges55:46
Medical informatics platform57:23
Reclassifying disease with data mining01:01:52
Data integration01:02:40
Links between phenomenology & biology - 101:03:30
Finding causal rules01:04:57
Links between phenomenology & biology - 201:05:27
Reverse engineering – to validate01:05:57
Informatics based approach01:06:44
MIP integrated view01:07:24
Thanks for listening01:07:56