Constrained Hidden Markov Models for Population-based Haplotyping
author:
Niels Landwehr,
University of Freiburg
Description
Analysis of genetic variation in human populations is critical to the understanding of the genetic basis for complex diseases. Although genomes of several species have been sequenced, it is still too expensive to sequence genomes of several individuals to analyze genetic variation. Furthermore, most of the genome is invariant among individuals.
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