The Challenge of Predicting Gene Function

author: Ross D. King, School of Computer Science, University of Manchester
published: Feb. 25, 2007,   recorded: June 2006,   views: 3642


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The biological sciences are undergoing an explosion in the amount of available data. New data analysis methods are needed to deal with the data. A central problem in bioinformatics is the assignment of function to sequenced open reading frames (ORFs). The most common approach is based on inferred homology using a statistically based se- quence similarity (SIM) method e.g. PSI-BLAST.

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