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Bayesian Inference of transcription factor activity - an application to the fission yeast cell cycle
Published on Sep 07, 20073734 Views
When modeling genetic regulatory interactions, it is often assumed that the mRNA expression of a transcription factor is a reliable proxy for the regulatory activity of that transcription factor. Th
Chapter list
Towards Bayesian inference in multiple-input motifs00:00
Overview00:09
Previously.....TFA inference in SIMs00:37
G/M2 Transition in fission yeast - part 102:17
G/M2 Transition in fission yeast - part 203:50
Competitive transcription factors04:10
mRNA production05:26
Stochastic Quasi-Steady-State assumption - part 107:13
Stochastic Quasi-Steady-State assumption - part 209:10
Competitive transcription factors10:25
Examples - how good is the approximation? - part 111:25
Examples - how good is the approximation? - part 212:26
Example - inference - part 112:54
Example - inference - part 214:20
Conclusions and Future work14:50