Machine Learning in Computational Biology

Explaining Confounding Factors in eQTL Studies using a Dictionary of Latent Variables

author: Nicolò Fusi, School of Computer Science, The University of Manchester
published: Jan. 12, 2011, recorded: December 2010, views: 215

Slides

Slides
0:00	Explaining Confounding Factors in eQTLstudies using a Dictionary of Latent Variables
0:13	eQTL mapping (1)
0:25	eQTL mapping (2)
1:53	The good news
2:05	The bad news
2:31	PANAMA (Probabilistic ANalysis of MicroArray data)
3:23	PANAMA (Gene expression)
3:32	PANAMA
4:06	The likelihood
4:15	Obtain the marginal likelihood
4:38	PANAMA’s action is divided into two phases
4:54	Association testing
5:41	Experimental results
5:48	Simulated dataset
7:00	- Question
8:09	Panama experiments (missing slide)
8:36	PANAMA-ARD
9:11	Simulated dataset
9:40	Yeast dataset
10:18	Cis associations
10:44	Trans associations
10:58	Overall associations
11:43	Validation
12:56	Conclusions
13:33	- Questions

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