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Machine Learning, Support Vector Machines, and Large Scale Optimization Workshop

Learning interpretable SVMs for biological sequence classification

author: Sören Sonnenburg, Fraunhofer Institute Computer Architecture and Software Technology
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Slides
0:03 Learning interpretable SVMs for biological
0:32 Roadmap:
0:58 Biology: Detection of Splice Sites
2:09 Approach: String Kernel + SVM
3:45 Success
5:33 Gain
8:20 Reformulation: Multiple Kernel Learning
8:32 Biology: Detection of Splice Sites
9:05 Approach: String Kernel + SVM
9:54 Multiple Kernel Learning
10:47 Constraining the weights
11:57 Standard SVM Optimization Problem
12:09 MKL Optimization Problem I
13:23 MKL Optimization Problem II
15:30 MKL Optimization Problem II
17:59 The Semi-Infinite Linear Program I
18:23 The Semi-Infinite Linear Program II
18:59 Solving the SILP: Column Generation I
21:05 Solving the SILP: Column Generation II
21:38 Solving the SILP: Boosting I
22:59 Solving the SILP: Boosting I
23:21 Stability of the solution ?
24:52 Toy Dataset
28:27 Application to Acceptor splice sites
29:35 Conclusion

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