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Machine Learning in Systems Biology
Pascal

Towards Structured Output Prediction of Enzyme Function

coauthor: Juho Rousu, University of Helsinki
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Slides
0:00 Towards Stuctured Prediction of Enzyme
0:58 Predicting Enzyme Function
3:32 Structured Output Prediction of Enzyme Function
3:48 Predicting Enzyme Function
4:04 Structured Output Prediction of Enzyme Function
6:28 Max-Margin Regression - MMR
8:57 Input Feature Maps
10:45 GTG Features
13:27 Output Feature Map: EC-Hierarchy
15:18 Good News First
17:10 However
18:39 Nearest Neighbor Does Very Well, Too
19:27 So What Is Going On Here?
21:45 Experiments: Gold Standard Dataset
23:35 Towards More Fine-Grained Function Representations
24:30 Reaction Kernels
26:18 - Questions

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