Introduction to the bioinformatics of cancer: high-throughput sequencing of the genome, epigenome and transcriptome

author: Valentina Boeva, Institut Curie
published: Feb. 17, 2015,   recorded: September 2014,   views: 2113


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In this presentation, I will introduce bioinformatics approaches to study genetic, epigenetic and transcriptome variations in cancer. I demonstrate how we can analyze whole genome, exome sequencing and amplicon sequencing data in order to find small mutations, copy number changes and large structural variants in cancer DNA. I will talk about the analysis of RNA-seq and ChIP-seq data in cancer studies.

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