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Machine Learning over Text & Images - Autumn School

Joint Mining of Biological Text and Images: Case Studies

author: Robert Murphy, Carnegie Mellon University
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Slides
0:00 Joint Mining of Biological Text and Images: Case Studies
0:31 Systems Biology and Location Proteomics
2:42 Automated Interpretation
3:06 Supervised Learning of High-Resolution Subcellular Location Patterns
3:20 The Challenge
4:13 Feature-based, Supervised learning approach
4:38 Boland & Murphy 2001
5:11 Machine Learning Methods
5:25 Evaluating Classifiers
5:45 2D Classification Results
6:19 Human Classification Results
6:54 Computer vs. Human
7:15 3D HeLa cell images
8:58 Unsupervised Learning to Identify High-Resolution Protein Patterns
9:31 Location Proteomics
10:19 What Now?
10:53 Chen et al 2003; Chen and Murphy 2005
12:14 slide18
12:16 Nucleolar Proteins
12:22 Punctate Nuclear Proteins
12:28 Predominantly Nuclear Proteins with Some Punctate Cytoplasmic Staining
12:35 Nuclear and Cytoplasmic Proteins with Some Punctate Staining
13:06 Image Content-based Retrieval and Interpretation of Micrographs from On-line Journal Articles
17:03 Objectives of SLIF
18:04 Example page from biomedical literature
19:14 SLIF components
20:32 Overview: Image processing in SLIF
22:32 Overview: Image processing in SLIF01
24:13 Overview: Text Processing in SLIF Find entity names in text, and panel labels in text and the image. Match panels labels in text to panel labels on the image. Associate entity names to textual pane
25:25 Some major challenges
39:28 Graphical model: Panel typing
48:10 SLIF programmatic interface
48:25 Acknowledgments
48:43 Brian Athey (UMich), CMU: Bob Murphy

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