The l-bfgs limited-memory quasi-Newton method is the algorithm of choice for optimizing the parameters of large-scale log-linear models with L2 regularization, but it cannot be used for an L1-regularized loss due to its non-differentiability whenever some parameter is zero. Eficient algorithms have been proposed for this task, but they are impractical when the number of parameters is very large. We present an algorithm OrthantWise Limited-memory Quasi-Newton (owlqn), based on l-bfgs, that can eficiently optimize the L1-regularized log-likelihood of log-linear models with millions of parameters. In our experiments on a parse reranking task, our algorithm was several orders of magnitude faster than an alternative algorithm, and substantially faster than lbfgs on the analogous L2-regularized problem. We also present a proof that owl-qn is guaranteed to converge to a globally optimal parameter vector.