The coupling of strain evolution and disease dynamics
published: Oct. 15, 2008, recorded: September 2008, views: 2861
Report a problem or upload filesIf you have found a problem with this lecture or would like to send us extra material, articles, exercises, etc., please use our ticket system to describe your request and upload the data.
Enter your e-mail into the 'Cc' field, and we will keep you updated with your request's status.
Influenza A is characterized by seasonal outbreaks and a gradual genetic, yet discontinuous antigenic evolution (antigenic "cluster jumps" occuring every 4-7 years, with a large seasonal epidemic as a result of lacking immunity among the population).The interplay between viral mutations and an age-group-specific human immune response is modelled here, trying to account for the observed phenomena and to predict next season's epidemic strain from the dynamics of the previous year.
Link this pageWould you like to put a link to this lecture on your homepage?
Go ahead! Copy the HTML snippet !