Mechanism for Top-down Control of Working Memory Capacity

author: Albert Compte, IDIBAPS
published: Oct. 17, 2008,   recorded: September 2008,   views: 6739
Categories

Related Open Educational Resources

Related content

Report a problem or upload files

If you have found a problem with this lecture or would like to send us extra material, articles, exercises, etc., please use our ticket system to describe your request and upload the data.
Enter your e-mail into the 'Cc' field, and we will keep you updated with your request's status.
Lecture popularity: You need to login to cast your vote.
  Bibliography

Description

Working memory relies on the activation of both prefrontal and parietal cortex, possibly with prefrontal cortex exerting top-down control. However, there is still no mechanistic description of either capacity limitations or top-down control of maintenance of information in working memory. Here, we propose that lateral inhibition in parietal cortex limits mnemonic capacity. However, at high loads, this inhibition can be counteracted by excitatory input from prefrontal cortex, thus boosting parietal capacity. We formulate this computationally in a biophysical cortical microcircuit model, and conceptualize it in a mathematical equation. Predictions from the model were confirmed in an fMRI study. The model provides a mechanistic framework for understanding top-down control of working memory, and specifies two different contributions of prefrontal and parietal cortex to working memory capacity.

Link this page

Would you like to put a link to this lecture on your homepage?
Go ahead! Copy the HTML snippet !

Write your own review or comment:

make sure you have javascript enabled or clear this field: