Integrated analysis of miRNA and mRNA expression profiling as a tool to identify prognostic markers and associated pathways
published: May 9, 2012, recorded: September 2010, views: 240
Report a problem or upload filesIf you have found a problem with this lecture or would like to send us extra material, articles, exercises, etc., please use our ticket system to describe your request and upload the data.
Enter your e-mail into the 'Cc' field, and we will keep you updated with your request's status.
Micro-RNA (miRNA) expression and function have been shown to be highly dependent upon the experimental system considered. Here we present a systems view of miRNA expression analysis in-vivo that may assist in identification of effective novel therapeutic approaches. Specifically, we show how combined information regarding expression of mature micro-RNAs (miRNA) and of the miRNA host-gene (upstream) and miRNA targets (downstream) can be integrated into analysis of clinical samples, to both discover and assess prognostic miRNAs and their associated pathways, and to discover novel miRNA targets.
Download slides: cancerbioinformatics2010_buffa_iam_01.pdf (369.9 KB)
Link this pageWould you like to put a link to this lecture on your homepage?
Go ahead! Copy the HTML snippet !