Boštjan Vasle graduated from the Faculty of Economics, University of Ljubljana in 1994 and continued his studies at the Central European University in Budapest, where he completed a master's degree in monetary policy in 1997.

His professional career started at the Ministry of Finance. In 2000, he moved to the Institute of Macroeconomic Analysis and Development, where his main areas of work were price and monetary policies. One of the Institute's major projects in which he was involved at that time was the preparation of economic policy measures that led to the lowering of inflation in Slovenia and the subsequent successful adoption of the euro.

In 2006 he was engaged at the Government Office for Growth where he supervised the implementation of economic reforms. As Head of the Department for Economic Reforms he was responsible for the coordination of measures aimed at restructuring public finances, improving competitiveness, increasing the efficiency of higher education, the privatisation and development of financial markets, and aligning reforms with the Lisbon Strategy. At the end of 2006, after the implementation of the first package of economic reforms, he returned to IMAD and assumed its leadership in December 2007.