Tailoring biomolecular interactions of core-shell nanoparticles and their application to magnetoresponsive drug delivery vehicles

author: Erik Reimhult, University of Natural Resources and Life Sciences (BOKU)
published: July 9, 2018,   recorded: May 2018,   views: 397
Categories

Slides

Related Open Educational Resources

Related content

Report a problem or upload files

If you have found a problem with this lecture or would like to send us extra material, articles, exercises, etc., please use our ticket system to describe your request and upload the data.
Enter your e-mail into the 'Cc' field, and we will keep you updated with your request's status.
Lecture popularity: You need to login to cast your vote.
  Bibliography

Description

Core-shell nanoparticles can be used in biomedical applications, e.g., as biomedical imaging contrast agents, for hyperthermia and in drug delivery, as well as for biotechnological applications such as separation and purification. Unique functions can be achieved by using nanoscale inorganic cores, such as superparamagnetic iron oxide nanocrystals for controlling interactions with magnetic fields. Using densely grafted polymer shells with controlled morphology and topology interactions with proteins can be tuned in biological fluids and we show this ultimately affects cell interaction and uptake. However, to enable advanced materials functions in a biological environment, e.g. specific binding, aggregation and drug release, integration of grafted stimuli-responsive polymer shells or into structured amphiphile and polymer assemblies must be carefully designed.

Link this page

Would you like to put a link to this lecture on your homepage?
Go ahead! Copy the HTML snippet !

Write your own review or comment:

make sure you have javascript enabled or clear this field: