Lecture 22 - Tissue Engineering

author: W. Mark Saltzman, Department of Biomedical Engineering, School of Engineering and Applied Science, Yale University
recorded by: Yale University
published: Jan. 4, 2011,   recorded: March 2008,   views: 3163
released under terms of: Creative Commons Attribution No Derivatives (CC-BY-ND)

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Professor Saltzman motivates the need for tissue engineering, and describes the basic elements of the tissue engineering approach. Professor Saltzman defines three different types of tissue transplants: autografts, allografts, and xenografts. An online resource for organ donors/recipients is presented, which stresses the great need for donors, and the important contribution of tissue engineering in producing/growing organs that can be used for this purpose. Next, Professor Saltzman compared drug and gene therapy, and discusses the use of stem cell in tissue engineering for wound healing. The need for compatible biomaterials to support growth and differentiation of stem cells into functional organ is also highlighted.

Reading assignment:

Biomedical Engineering: Bridging Medicine and Technology, in preparation by Mark Saltzman (forthcoming by Cambridge University Press); chapter 16

Griffith, Linda G. and Gail Naughton. "Tissue Engineering -- Current Challenges and Expanding Opportunities." Science, Volume 295, (February 8), pp. 1009-14. 2002.
Langer, Robert and Joseph P. Vacanti. "Tissue Engineering." Science, New Series, Volume 260, Issue 5110 (May 14), pp. 920-926, 1993.


Summary and Key Concepts: Chapter 16 [PDF]

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