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The impact of upper motor neuron degeneration on respiration in wakefulness and sleep in amyotrophic lateral sclerosis

Published on Oct 01, 20151425 Views

Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of upper (UMN) and lower motor neurons (LMN), which eventually leads to respiratory insufficiency. The individual differences betwe

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Impact of upper motor neuron degeneration on respiration in wakefulness and sleep in amyotrophic lateral sclerosis00:00
Breathing: complex and vital00:15
Amyotrophic Lateral Sclerosis - 101:05
Amyotrophic Lateral Sclerosis - 202:22
Methods: Outcome measures03:26
Results: Patient characteristics05:03
Results: Grouping of patients05:30
Results: Volitional control of breathing06:09
Results: Respiratory drive06:38
Results: Blood gas analysis06:54
Results: Proportion of REM sleep07:27
Main puzzle07:45
Answer: Acclimatization08:08
O.K. but ...09:06
Because ... - 109:29
Because ... - 211:02
Take home message11:59
Thank you!14:02