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Neural coding of upshifted, downshifted, and blocked outcomes in the rat (lateral) orbitofrontal cortex

Published on Jul 28, 20151741 Views

There is much debate over what information about outcomes the orbitofrontal cortex encodes in order to support outcome-guided behavior. One model is that the primary job of neurons there is to distil

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The good, the bad, and the ugly: neural coding of upshifted, downshifted and blocked cues in the orbitofrontal cortex00:00
Choices - 100:52
Choices - 200:55
Choices - 301:10
Choices - 401:27
Choices - 502:38
Choices - 603:25
Blocking and Unblocking - 104:28
Blocking and Unblocking - 204:33
Blocking and Unblocking - 305:50
Blocking and Unblocking - 406:39
Learning ... - 108:26
Learning ... - 208:44
Probe for value based unblocking…. - 110:02
Probe for value based unblocking…. - 210:03
Probe for value based unblocking…. - 310:18
Probe for value based unblocking…. - 410:19
So is that consistent with correlates in OFC?10:50
Behavioral procedures for recording - 111:30
Behavioral procedures for recording - 212:01
Behavioral procedures for recording - 312:25
Behavioral procedures for recording - 413:19
Behavioral procedures for recording - 514:05
Behavioral procedures for recording - 614:39
Predictions for odor firing - 115:00
Predictions for odor firing - 215:07
Predictions for odor firing - 315:13
Predictions for odor firing - 415:20
Predictions for odor firing - 515:31
Predictions for odor firing - 615:38
Many OFC neurons (~1/3) fired to the critical odor cues - 116:05
Many OFC neurons (~1/3) fired to the critical odor cues - 216:15
Many OFC neurons (~1/3) fired to the critical odor cues - 316:48
Many OFC neurons (~1/3) fired to the critical odor cues - 417:10
Many OFC neurons (~1/3) fired to the critical odor cues - 517:20
Many OFC neurons (~1/3) fired to the critical odor cues - 617:35
Remaining neurons showed associative firing to the predictive odors - 118:24
Remaining neurons showed associative firing to the predictive odors - 218:34
Remaining neurons showed associative firing to the predictive odors - 318:49
Remaining neurons showed associative firing to the predictive odors - 419:11
Activity to valued and value-less cues was similar ... - 119:17
Activity to valued and value-less cues was similar ... - 219:35
Activity to valued and value-less cues was similar ... - 319:44
Activity to valued and value-less cues was similar ... - 419:57
Activity to valued and value-less cues was similar ... - 520:10
Activity to valued and value-less cues was similar ... - 620:31
OFC neurons acquired activity to the cue predicting new reward features but no change in value - 121:00
OFC neurons acquired activity to the cue predicting new reward features but no change in value - 221:57
OFC neurons acquired activity to the cue predicting new reward features but no change in value - 322:23
OFC neurons acquired activity to the cue predicting new reward features but no change in value - 422:27
Behavioral procedures for recording - 123:22
Behavioral procedures for recording - 223:31
Behavioral procedures for recording - 323:36
Behavioral procedures for recording - 423:42
Behavioral procedures for recording - 524:01
Behavioral procedures for recording - 624:03
Behavioral procedures for recording - 724:06
Behavioral procedures for recording - 824:12
Behavioral procedures for recording - 924:18
Behavioral procedures for recording - 1024:37
Behavioral procedures for recording - 1124:51
Behavioral procedures for recording - 1225:26
Again many neurons fired to cue predicting more reward - 126:24
Again many neurons fired to cue predicting more reward - 226:37
Including some neurons that seem to code value ... - 127:00
Including some neurons that seem to code value ... - 227:10
Including some neurons that seem to code value ... - 327:35
Including some neurons that seem to code value ... - 427:47
Many neurons (half) fired to cue predicting more reward … - 128:07
Many neurons (half) fired to cue predicting more reward … - 228:10
Many neurons (half) fired to cue predicting more reward … - 328:45
Many neurons (half) fired to cue predicting more reward … - 428:49
Many neurons (half) fired to cue predicting more reward … - 529:02
Many neurons (half) fired to cue predicting more reward … - 629:17
Many neurons (half) fired to cue predicting more reward … - 729:19
Many neurons (half) fired to cue predicting more reward … - 829:40
Many neurons (half) fired to cue predicting more reward … - 929:42
So type of information does the orbitofrontal cortex contribute?30:39
Acknowledgements31:59