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Maximum Likelihood Estimation for a Gene Regulatory Network Defined by Differential Equations
Published on Feb 4, 20258354 Views
Gene regulation may be described by a set of deterministic differential equations describing the time rate evolution of the gene product concentrations, and containing parameters accounting for the re
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Presentation
Parameter estimation for gene regulatory networks defined by differential equations00:01
Outline00:12
Gene Regulatory Network00:44
Mathematical formalisms01:00
ODE’s formalism04:25
Example: Reaction-diffusion model05:08
Proteomic data06:52
Statistical model08:11
Maximum Likelihood Estimation10:24
Asymptotic properties13:37
Drosophila case14:48
Summary and Perspectives17:02
Bibliography18:10
Acknowledgements18:17