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Nanoparticles and their Relevance in Health Care
Published on Jun 15, 20112846 Views
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Chapter list
Nanoparticles and their relevance in health care00:00
Why do we need "Nano" for medicine?00:56
Nanomedicine is one of the most important sub-discipline02:36
Nanomedicine circle03:51
Nanoparticles as medicine – are effective and safe??04:54
The use of nano-scale science for the benefit of the patient06:53
Focus on07:26
Engineered nanoparticles, pharmacokinetics and biodistribution08:17
Nanoparticle drug delivery system09:03
Challenges and optimism for engineered NPs09:47
Nanoparticles function and characterization11:21
3D height images of SLN using AFM12:39
Biodistribution of nanoparticles12:42
Pharmacokinetics of NPs13:43
Internalization and translocation of NPs14:54
Interactions of SLN with the cells15:13
Interactions of SLN with the cells and uptake15:15
Passing of NPs over the cell-membrane15:57
Rapid uptake of SLNs into the HEK 293 cells17:05
Moving of NPs inside the cells18:06
Internalization of SLN19:56
Trafficking of SLN after cell uptake19:56
Characteristics of new fluorescent dye SPP21:06
Visualization of SLN in cells using SPP or C22:09
SLN-SPP uptake into the cells22:44
Intracellular positioning of SLN-SPP23:46
Targeting cancer cells using NPs coated with mAb27:35
Multifunctional NP targeted to cancer cell membranes27:48
Preparation of mAb-coated NPs with cystatin28:36
Cell targeting and internalization of mAb-NPs29:44
Formulation of safe NPs32:37
Cytotoxicity of nanoparticles33:25
Effects of NPs on cell health34:34
Effect of stabilizer34:51
Metabolic activity of HEK 293 cells after interaction with SLN36:16
Alterations in nuclei morphology of HEK293 cells36:45
Can particles at nanoscale result in safe drug delivery?38:10
Viability of keratinocytes treated38:14
SEM images of keratinocytes topography40:02
TEM images of Zno, TiO2 in cells40:57
Morphology of cell nuclei and actin filaments after long-term exposure43:54
Bio nano materials44:44
Cancer nanotechnology45:23
Nanotheranostics and image-guided DD45:44
Targeted imaging and therapy of brain cancer using theranostic NP46:27
From FDA news48:16
Resolving the nanoparticles paradox49:03
Thank you for your attention53:39