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Using PPI Networks in hierarchical multi-label classification trees for gene function prediction

Published on Oct 23, 20123817 Views

Daniela Stojanova

**Motivation:** Catalogs, such as Gene Ontology (GO) and MIPS-FUN, assume that functional classes are organized hierarchically (general functions include more specific functions). This has recently

MLSB 2012 - Basel

Related categories

GeneticsClassification

Chapter list

Using PPI Network Autocorrelation in Hierarchical Multi-label Classification Trees for Gene Function Prediction00:00
The Task00:06
The Context01:45
The Problem02:15
Autocorrelation 02:56
Network autocorrelation of gene functions03:53
The Basic Idea06:09
The Basic Idea: learning NHMC07:26
Autocorrelation measure08:10
Algorithm outline09:35
Datasets10:27
Results11:41
mlsbComparison CLUS-HMC &NHMC12:07
Comparison to other methods13:13
Comparison using different PPI networks13:35
Contributions15:12
Conclusions15:38
Future Work16:53
Q & A17:32