0.25
0.5
0.75
1.25
1.5
1.75
2
Efficient, data-based network inference using a linear programming approach
Published on Oct 23, 20122921 Views
**Motivation:** In the recent years, technical developments enabled the facilitated measurements of biological high-throughput data. This results in a qualitative and a quantitative improvement of th
Related categories
Chapter list
Efficient Network Inference using a Linear Programming Approach00:00
Multiple pathways to oncogenesis00:31
ERBB signaling pathway02:02
Trastuzumab Pathway03:00
RNA interference (RNAi)04:28
The ERBB family of receptor tyrosine kinase05:32
Network Inference - 106:10
Network Inference - 207:18
LP Model assumptions08:41
LP Model constraints09:20
LP-SF Model11:30
Simulations12:52
Results 10-node networks14:15
Results large-scale networks14:49
Run time15:11
Noisy Data: 10 node-nw15:55
Incomplete Data: 10 node-nw16:27
LP Model constraints if prior knowledge is available17:03
Prior knowledge integration: 10 node-nw18:18
ERBB signaling data - 119:00
ERBB signaling data - 219:24
Summary20:08
Thank you for your attention!22:04