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Targeted retrieval of gene expression measurements using regulatory models
Published on Oct 23, 20122677 Views
**Motivation:** Large public repositories of gene expression measurements offer the opportunity to position a new experiment into the context of earlier studies. While previous methods rely on exper
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Chapter list
Targeted Retrieval of Gene Expression Measurements Using Regulatory Models00:00
Motivation00:17
What is a suitable similarity measure?01:32
This approach: Model-based targeted retrieval03:41
System for targeted retrieval05:27
Targeted gene expression model06:11
Model-based similarity measure07:51
Case study on plant osmotic stress11:20
Case study on plant stress12:22
Precision-recall analysis14:23
Osmotic stress network analysis15:12
Model-based comparison of measurements16:40
Discriminative target genes17:31
Discussion18:24