en
0.25
0.5
0.75
1.25
1.5
1.75
2
Systems Cancer Chronotherapeutics: In Vitro Molecular Chronopharmacology of the Anticancer Drug Irinotecan
Published on 2014-07-211689 Views
Chronotherapeutics aim at improving treatment outcomes through the delivery of medicines according to the Circadian Timing System (CTS), a complex hierarchical and dynamic network system involving a
Presentation
Systems Cancer Chronotherapeutics :in Vitro Molecular Chronopharmacology Of The Anticancer Drug Irinotecan00:00
Outline00:18
Molecular-basedpersonalizationof cancer chronotherapeutics00:46
In vitro circadianstudies01:35
Irinotecan (CPT11)03:34
CPT11 Pharmacokinetics(PK) - 103:55
CPT11 Pharmacokinetics(PK) - 204:45
CPT11 Pharmacodynamics(PD) - 105:04
CPT11 Pharmacodynamics(PD) - 205:59
CPT11 molecularPK-PD - 107:01
CPT11 molecularPK-PD - 207:22
Irinotecan Molecular Chronopharmacology In Caco-2 Cells07:48
mRNA circadian rhythms07:56
CPT11 PK in Caco-2 cells09:08
Circadian rhythms of CPT11 PD10:00
Model Of Irinotecan Molecular Chrono PK-PD10:44
Ordinarydifferentialequations11:07
Mathematical model for protein circadian rhythm11:40
ScilabTutorial - 112:08
ScilabTutorial - 213:12
CPT11 molecular PK-PD14:24
ScilabTutorial - 314:35
ScilabTutorial - 415:01
ScilabTutorial: Exercise 1 - 117:01
ScilabTutorial: Exercise 1 - 217:16
ScilabTutorial: Exercise 1 - 317:17
ScilabTutorial: Exercise 2 - 118:12
ScilabTutorial: Exercise 2 - 220:01
Scilab Tutorial - 520:55
Scilab Tutorial - 622:05
Scilab Tutorial - 723:17
Scilab Tutorial - 823:21
Scilab Tutorial - 923:49
Scilab Tutorial - 1024:03
Conclusions of the in vitro study24:09