en
0.25
0.5
0.75
1.25
1.5
1.75
2
Systems Cancer Chronotherapeutics: In Vitro Molecular Chronopharmacology of the Anticancer Drug Irinotecan
Published on Jul 21, 20141686 Views
Chronotherapeutics aim at improving treatment outcomes through the delivery of medicines according to the Circadian Timing System (CTS), a complex hierarchical and dynamic network system involving a
Chapter list
Systems Cancer Chronotherapeutics :in Vitro Molecular Chronopharmacology Of The Anticancer Drug Irinotecan00:00
Outline00:18
Molecular-basedpersonalizationof cancer chronotherapeutics00:46
In vitro circadianstudies01:35
Irinotecan (CPT11)03:34
CPT11 Pharmacokinetics(PK) - 103:55
CPT11 Pharmacokinetics(PK) - 204:45
CPT11 Pharmacodynamics(PD) - 105:04
CPT11 Pharmacodynamics(PD) - 205:59
CPT11 molecularPK-PD - 107:01
CPT11 molecularPK-PD - 207:22
Irinotecan Molecular Chronopharmacology In Caco-2 Cells07:48
mRNA circadian rhythms07:56
CPT11 PK in Caco-2 cells09:08
Circadian rhythms of CPT11 PD10:00
Model Of Irinotecan Molecular Chrono PK-PD10:44
Ordinarydifferentialequations11:07
Mathematical model for protein circadian rhythm11:40
ScilabTutorial - 112:08
ScilabTutorial - 213:12
CPT11 molecular PK-PD14:24
ScilabTutorial - 314:35
ScilabTutorial - 415:01
ScilabTutorial: Exercise 1 - 117:01
ScilabTutorial: Exercise 1 - 217:16
ScilabTutorial: Exercise 1 - 317:17
ScilabTutorial: Exercise 2 - 118:12
ScilabTutorial: Exercise 2 - 220:01
Scilab Tutorial - 520:55
Scilab Tutorial - 622:05
Scilab Tutorial - 723:17
Scilab Tutorial - 823:21
Scilab Tutorial - 923:49
Scilab Tutorial - 1024:03
Conclusions of the in vitro study24:09