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Biological relevance of active gel theory
Published on 2016-04-051821 Views
Much of the cell mechanics, morphology and motility is determined by the dynamical properties of an actin network moving under the action of molecular motors and by a continuous process of polymerizat
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Presentation
Biological relevance of active gel theory00:00
Actin - based dynamics03:26
Many microscopic mechanisms04:55
Generalized hydrodynamics05:59
Harvard choice - 109:15
Harvard choice - 210:45
Harvard choice - 311:36
Contractility measured in units of Pascal - 212:45
Nematic hydrodynamics13:30
Spontaneous Frederiks transition - 114:07
Spontaneous Frederiks transition - 215:26
Topological singularities17:41
Spontaneously moving topological singularity17:53
Microtubules+motors18:14
Actomyosin contractility rotates the cell nucleus18:37
Control19:13
Pure Shear (Elongational Flow)20:00
Actin = 020:40
Xenopus egg wound healing - 120:59
Xenopus egg wound healing - 221:38
Want to describe - 122:29
Want to describe - 223:48
Cytokinesis25:48
Challenges27:53
Contractility generates flow30:17
Movie31:58
Sand - dollar zygote32:25
Cell division success/failure32:53
C elegans33:26
Non monotonic constriction rate34:18
Changing turnover - 134:48
Changing turnover - 235:43
Explains39:20
Untitled39:21
Nematic tissues40:44
Spontaneous Frederiks transition - 343:53
Spontaneous Frederiks transition - 444:29
Spontaneous Frederiks transition - 545:33
A unique and robust approach to many different phenomena47:32