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Dissecting the cell-type specific contribution of EHMT1 to neuronal network function using IPSC-derived brain models
Published on Jun 14, 202322 Views
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Chapter list
Understanding the cell-type specific function of EHMT1 in neuronal network function00:00
iPSC-derived models for translational studies: Opportunities and challenges - 100:53
iPSC-derived models for translational studies: Opportunities and challenges - 203:33
iPSC-derived models for translational studies: directed differentiation04:54
Fast protocol05:28
Measuring neural network activity of iPSC-derived networks - 107:00
Measuring neural network activity of iPSC-derived networks - 208:17
Probing for E/I balance in human pluripotent stem cell-derived neuronal networks09:05
Gaba09:55
iGABAergic neurons exhibit scalable functional inhibitory control10:28
Contribution of excitation and inhibition to Kleefstra syndrome neuronal network phenotypes12:11
Delayed GABAergic maturation in Kleefstra neuronal networks14:35
How do findings in a dish translate to in vivo?16:56
Altered development of GABAergic neurons in EHMT1+/- mice?17:37
Expression of EHMT119:14
Investigating the cell type-specific function of EHMT1 using iPSC models19:38
BRAINmodel - 121:35
BRAINmodel - 222:09
BRAINmodel - 322:21
BRAINmodel - 423:39
BRAINmodel - 524:09
Thank you25:33