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Knowledge Integration for Disease Characterization: A Breast Cancer Example
Published on 2018-11-222739 Views
With the rapid advancements in cancer research, the information that is useful for characterizing disease, staging tumors, and creating treatment and survivorship plans has been changing at a pace tha
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Presentation
Knowledge Integration for Disease Characterization: A Breast Cancer Example00:00
Goals of this resource00:31
Our workflow - 1 01:15
Our workflow - 202:11
Cancer Staging is Evolving! 02:19
Cancer Staging Ontology – A High Level View - 103:57
Cancer Staging Ontology – A High Level View - 204:12
Cancer Staging Ontology – A High Level View - 304:49
Cancer Staging Ontology – A High Level View - 404:51
Cancer Staging Ontology – A High Level View - 504:59
Stage Group Classifications - 105:13
Stage Group Classifications - 205:25
Stage Group Classifications - 305:37
Translating Staging Criteria into Structured Mappings - 105:51
Translating Staging Criteria into Structured Mappings - 206:01
Translating Staging Criteria into Structured Mappings - 306:24
Translating Staging Criteria into Structured Mappings - 406:29
Cancer Staging Ontology06:35
Our workflow - 307:02
Our workflow - 407:03
Knowledge Curation with Semantic Data Dictionaries07:13
Example small subset of the raw data from CIViC on diseases, drugs and genes07:32
Corresponding Semantic Data Dictionary - 108:08
Corresponding Semantic Data Dictionary - 208:16
Corresponding Semantic Data Dictionary - 308:26
Codebook for a subset of the rows in the CIViC dataset on diseases, drugs and genes - 108:44
Codebook for a subset of the rows in the CIViC dataset on diseases, drugs and genes - 209:24
Codebook for a subset of the rows in the CIViC dataset on diseases, drugs and genes - 309:36
Hierarchy of the Tumor Size (T) Classes - 109:37
Hierarchy of the Tumor Size (T) Classes - 209:45
Hierarchy of the Tumor Size (T) Classes - 309:47
Hierarchy of the Tumor Size (T) Classes - 410:18
Our workflow - 510:19
Our workflow - 610:21
Deductive Inference Agent10:38
Integrated Breast Cancer Knowledge Graph11:13
Our workflow - 712:04
Our workflow - 812:05
Personalized Treatment Agent - Patient “D” - 112:13
Personalized Treatment Agent - Patient “D” - 212:38
Personalized Treatment Agent - Patient “D” - 312:57
Personalized Treatment Agent - Patient “D” - 413:11
Personalized Treatment Agent - Patient “D” - 513:27
Personalized Treatment Agent - Patient “D” - 613:28
Personalized Treatment Agent - Patient “D” - 713:40
Evaluation14:15
Resource Contributions14:57
Thank you!15:33