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Knowledge Integration for Disease Characterization: A Breast Cancer Example
Published on Nov 22, 20182735 Views
With the rapid advancements in cancer research, the information that is useful for characterizing disease, staging tumors, and creating treatment and survivorship plans has been changing at a pace tha
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Chapter list
Knowledge Integration for Disease Characterization: A Breast Cancer Example00:00
Goals of this resource00:31
Our workflow - 1 01:15
Our workflow - 202:11
Cancer Staging is Evolving! 02:19
Cancer Staging Ontology – A High Level View - 103:57
Cancer Staging Ontology – A High Level View - 204:12
Cancer Staging Ontology – A High Level View - 304:49
Cancer Staging Ontology – A High Level View - 404:51
Cancer Staging Ontology – A High Level View - 504:59
Stage Group Classifications - 105:13
Stage Group Classifications - 205:25
Stage Group Classifications - 305:37
Translating Staging Criteria into Structured Mappings - 105:51
Translating Staging Criteria into Structured Mappings - 206:01
Translating Staging Criteria into Structured Mappings - 306:24
Translating Staging Criteria into Structured Mappings - 406:29
Cancer Staging Ontology06:35
Our workflow - 307:02
Our workflow - 407:03
Knowledge Curation with Semantic Data Dictionaries07:13
Example small subset of the raw data from CIViC on diseases, drugs and genes07:32
Corresponding Semantic Data Dictionary - 108:08
Corresponding Semantic Data Dictionary - 208:16
Corresponding Semantic Data Dictionary - 308:26
Codebook for a subset of the rows in the CIViC dataset on diseases, drugs and genes - 108:44
Codebook for a subset of the rows in the CIViC dataset on diseases, drugs and genes - 209:24
Codebook for a subset of the rows in the CIViC dataset on diseases, drugs and genes - 309:36
Hierarchy of the Tumor Size (T) Classes - 109:37
Hierarchy of the Tumor Size (T) Classes - 209:45
Hierarchy of the Tumor Size (T) Classes - 309:47
Hierarchy of the Tumor Size (T) Classes - 410:18
Our workflow - 510:19
Our workflow - 610:21
Deductive Inference Agent10:38
Integrated Breast Cancer Knowledge Graph11:13
Our workflow - 712:04
Our workflow - 812:05
Personalized Treatment Agent - Patient “D” - 112:13
Personalized Treatment Agent - Patient “D” - 212:38
Personalized Treatment Agent - Patient “D” - 312:57
Personalized Treatment Agent - Patient “D” - 413:11
Personalized Treatment Agent - Patient “D” - 513:27
Personalized Treatment Agent - Patient “D” - 613:28
Personalized Treatment Agent - Patient “D” - 713:40
Evaluation14:15
Resource Contributions14:57
Thank you!15:33