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Explainable Phenotype-Centric Drug Repurposing via Deep Reinforcement Learning
Published on Jun 13, 202331 Views
Chapter list
Explainable Drug Repurposing in Context via Multi-hop Reasoning00:00
Drug repurposing via multi-hop reasoning01:06
Drug repurposing via multi-hop reasoning 101:16
Drug Repurposing: use01:58
Multi-hop reasoning02:32
Drug repurposing via multi-hop reasoning: reinforcing path patterns03:29
Drug repurposing via multi-hop reasoning04:22
Drug repurposing via multi-hop reasoning 105:07
Drug repurposing via multi-hop reasoning 205:13
Including background knowledge05:25
Genotype to phenotype05:26
Phenotype to genotype06:19
Drug repurposing via multi-hop reasoning06:34
CoCo: Multi-hop reasoning Coherent with Context07:20
Multi-hop reasoning in context: method07:28
1. Automated genotype-phenotype annotation07:52
2. Multi-hop reasoning in context08:31
2. Multi-hop reasoning in context 108:39
2. Multi-hop reasoning in context 208:47
2. Multi-hop reasoning in context 309:03
Training insights09:11
Evaluation09:39
Quantitative & Qualitative Evaluation09:43
Quantitative Evaluation10:54
Quantitative Evaluation 111:10
Quantitative & Qualitative Evaluation11:36
Quantitative & Qualitative Evaluation 112:19
Quantitative & Qualitative Evaluation 212:44
Takeaways & future work13:09