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Tiresias: Predicting Drug-Drug Interactions Through Large-Scale Similarity-Based Link Prediction

Published on Jul 28, 20161592 Views

Drug-Drug Interactions (DDIs) are a major cause of preventable adverse drug reactions and a huge burden on public health and the healthcare system. On the other hand, there is a large amount of dru

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Chapter list

Tiresias: Predicting Drug-Drug Interaction Through Large-Scale Similarity-Based Link Predictions00:00
Adverse Drug Reactions pose a serious challenge to the healthcare system00:04
Similarity-based Drug-Drug Interaction (DDI) Predictions02:26
Limitations of Prior Work - 105:46
Limitations of Prior Work - 209:04
Limitations of Prior Work - 311:01
Overview12:51
13 Similarity Measures - 114:33
13 Similarity Measures - 215:34
Feature Generations17:51
Brief discussion on DDI Prevalence20:07
Experimental Evaluation: Retrospective Analysis (2011)20:29
Experimental Evaluation: 10-fold cross validation21:27
Demo22:21