Whole Animal Modeling: Network Perspectives

Published on Jul 02, 20123090 Views

Function Prediction in Complex Networks 2012 - Kavli Royal Society Centre

Whole Animal Modeling: Network perspectives00:00

The question05:04

The wiring diagram06:34

Head sensory neurons11:10

A feed-forward circuit?13:23

Sensory neurons & 1st layer interneurons14:06

1D Spatial Networks17:02

Body size constraints on nervous system21:22

Behavior in C. elegans: A top-down view25:06

From neural control to locomotion28:14

Previous models31:03

There’s more to life than crawling ...32:57

Does the worm need a groove to sustain a sinusoidal shape?34:29

Questions37:27

Testing the two gait hypothesis38:18

The "gelatin assay"38:20

Modulation of one gait38:44

A modeling challenge39:24

Building a model (1)39:27

Building a model (2)40:04

Passive body properties41:00

The forward locomotion circuit41:03

A minimal model42:26

The Motor Neuron42:33

More recent data ...43:21

Modeling Bistability in B-class motor neurons44:34

Simulation results44:37

Model results: intermediate conditions44:56

Beyond a single primitive45:12

Discussion Points45:25

Nematode evolution: the Ecdysozoa debate50:00