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1.25
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1.75
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ATP dependency of osmotically activated outwardly rectified current in the membrane of cytoplasmic droplets obtained from sporangiophore of model filamentous fungus Phycomyces blakesleeanus
Published on 2018-07-09385 Views
ORIC is outwardly rectified, rapidly inactivating anionic current that is activated in hypo-osmotic conditions in the membrane of cytoplasmic droplets obtained from sporangiophore of filamentous fungu
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ATP dependency of osmotically activated outwardly rectified current in the membrane of cytoplasmic droplets obtained from sporangiophore of model filamentous fungus Phycomyces blakesleeanus00:00
Only 6 cell membrane ion currents are characterized electrophysiologically in all filamentous fungi00:37
Our model system is membrane obtained from aerial hyphal cell – sporangiophore of Phycomyces blakeseeanus - 103:15
Our model system is membrane obtained from aerial hyphal cell – sporangiophore of Phycomyces blakeseeanus - 204:06
ORIC ≈ VRAC05:29
Without ATP ORIC rundown exponentially06:57
2mM intracellular ATP significantly slows ORIC rundown07:28
Mg2+ reduction further activates ORIC08:20
ATP modifies effects of ORIC inhibitors, A9C and NFA08:51
A9C and NFA are potent inhibitors of cell respiration and ATP synthesis10:40
Untitled11:24
Conclusions12:04