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Monovalent T-cell antigen receptor complexes drive T-cell antigen recognition

Published on Jul 09, 2018404 Views

T-cells recognize MHC-embedded antigenic peptide fragments (pMHCs) on antigen presenting cells (APCs) through their clonotypic T-cell antigen receptors (TCRs), which typically feature only moderate af

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Chapter list

Monomeric TCRs Drive T-Cell Antigen Recognition00:00
Fighting (currently) a common cold… - 100:07
Fighting (currently) a common cold… - 200:34
The T-cell receptor signalling complex - 102:02
The T-cell receptor signalling complex - 203:13
The T-cell receptor signalling complex - 303:45
The T-cell receptor signalling complex - 404:10
Model system for studying T-cells - 105:28
Model system for studying T-cells - 206:05
Model system for studying T-cells - 307:18
Model system for studying T-cells - 407:32
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 108:19
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 209:00
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 309:22
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 409:43
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 510:03
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 610:36
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 711:25
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 812:04
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 912:10
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 1012:22
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 1112:55
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 1214:32
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 1315:00
Laterally Mobile TCR/CD3 Complexes Feature One TCRb and Two CD3e Subunits - 1415:35
How to address immobile TCR/CD3 complexes? - 115:38
How to address immobile TCR/CD3 complexes? - 216:47
How to address immobile TCR/CD3 complexes? - 318:01
How to address immobile TCR/CD3 complexes? - 419:11
TCR oligomers at the inital contact of T-cells with bilayer ? - 119:19
TCR oligomers at the inital contact of T-cells with bilayer ? - 220:32
TCR oligomers at the inital contact of T-cells with bilayer ? - 320:53
TCR oligomers at the inital contact of T-cells with bilayer ? - 421:01
Conclusion - 121:07
Conclusion - 221:47
Thank you22:43