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Project MindScope: Large Scale Science for Mapping the Mind

Published on Dec 03, 20123007 Views

The Allen Institute is engaged in a ten year project to study the principles by which information is encoded, transformed and represented in the mammalian cerebral cortex and related structures. The g

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Chapter list

Project MindScope - Building Brain Observatories00:00
Seattle (1)00:01
Seattle (2)00:05
Seattle (3)00:35
The Allen Institute for Brain Science00:36
Observatories of the mind03:37
Astronomical Observatories04:15
The vision05:41
MindScope - Organization08:04
Understanding Coding08:30
Why is this difficult?09:47
Why Study Neocortex?17:41
Why Study the Mouse?22:25
Human - Mouse comparison24:13
Neurons - the Atoms of Consciousness25:16
The world’s smartest mouse25:57
Vision in the Mouse28:15
Contrast Detection29:14
Mouse Visual Cortex29:47
Connectional Atlas30:44
Serial 2P Tomography Imaging with Injection at VIS31:02
Injection Sites Distributed Throughout Major Brain Structures31:48
Cortical H ierarchy32:00
Retinal Cell Types (1)33:05
Retinal Cell Types (2)34:18
Retinal Cell Types (3)34:27
Retinal Cell Types (4)34:34
Near-Term Goals for Cell Types34:59
2-Photon Calcium Imaging in Behaving Animals36:32
Imaging 1,000 of Neurons36:41
Inter-areal functional connectivity in mouse visual cortex37:27
2PC Imaging and EM-based Anatomical Reconstruction37:31
What are the relationships between cell types, anatomy, and cortical function?38:07
Near-Term Goals for Neural Coding38:45
Brain Observatories38:53
Advanced Silicon Probes39:48
From Correlation to Causation40:30
Playing Piano on the Brain40:56
Computational Neuroanatomy41:49
Modeling, Analysis and Theory - Mike Hawrylycz42:49
Component Models42:50
System Models44:05
MindScope - Challenges44:06
MindScope - Challenges The Complexity of it All46:21