Introduction to bioinformatics

author: Gunnar Rätsch, Max Planck Institute
published: Aug. 20, 2007,   recorded: August 2007,   views: 51165


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I will start by giving a general introduction into Bioinformatics, including basic biology, typical data types (sequences, structures, expression data and networks) and established analysis tasks. In the second part, I will discuss the problem of predictive sequence analysis with Support Vector Machines (SVMs). I will introduce a series of kernels suitable for different analysis tasks. Furthermore I will discuss the basic data structures needed for large scale learning and how to combine kernels for heterogeneous data. In the third part, I will focus on Hidden Markov models and discriminative alternatives like Conditional Random Fields and Hidden Markov SVMs suitable for segmentation tasks frequently appearing in Bioinformatics. In the last part I will present three applications in greater detail: A large margin alignment algorithm, computational gene finding and the identification of polymorphisms from resequencing arrays.

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Reviews and comments:

Comment1 Chandan Datta, September 3, 2007 at 4:06 p.m.:

I hope Part 1 is uploaded soon

Comment2 Manuel, November 20, 2007 at 9:33 a.m.:

Great, but the audio could have been better

Comment3 macias, January 6, 2008 at 8:11 p.m.:

I can download part 1 but I cannot download any other part:
Resolving for AF_INET6...
Couldn't resolve name for AF_INET6:
Resolving for AF_INET...
Connecting to server[]: 80...
Cache size set to 320 KBytes

Comment4 CLEMENT MWEYA, July 31, 2008 at 3:06 p.m.:

I really need to watch these video lectures but my internet connection in Tanzania has a very low speed. I can't even watch 1 minute online.
I need your help. Need to download these video lectures so as I can be able to watch them and revise.
Will help me a lot to integrate my basic science with bioiformatics
MSc Medical Parasitology and Entomology student
my email address is

Comment5 Bipin Singh University of Allahabad, September 10, 2008 at 8:05 p.m.:

the video lectures are extremely good but there is some audio error at some point which could br resolved.Please provide the videos in .zip for easy and fast download.

Comment6 Saad The Islamia Univ Pakistan, December 4, 2008 at 11:38 p.m.:

Excellent Tutorial ... Thanks for upload

Comment7 m.rezaei, February 6, 2009 at 10:25 p.m.:

Due to low connection speed, it was impossible for me to
watch this video. Is it possible to download these videos?
I would appreciate if this is the case.

Comment8 rk, April 18, 2010 at 11:51 p.m.:

all the images point to the same url:

so, i don't see any way for me to watch lecture#2 and above? i have watched 1st one so far.

please tell me how to watch the others?

Comment9 Davor (staff), April 19, 2010 at 9:34 a.m.:

@rk, do you see the 6 pictures of the speaker underneath the first video? Try to click on the picture that says "Part 2".

@m.rezaei, unfortunately the videos are not downlodable at the moment but we expect to change this policy in the next few months

Comment10 gang gao, September 13, 2010 at 3:32 p.m.:

very good lecture

Comment11 Babita Pandey, December 5, 2013 at 12:30 p.m.:

Due to low connection speed, it was impossible for me to
watch this video. Is it possible to download these videos ?
I would appreciate if this is the case.

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