CHEM 125b: Freshman Organic Chemistry II

CHEM 125b: Freshman Organic Chemistry II

38 Lectures · Feb 1, 2011

About

This is a continuation of Freshman Organic Chemistry I (CHEM 125a), the introductory course on current theories of structure and mechanism in organic chemistry for students with excellent preparation in chemistry and physics. This semester treats simple and complex reaction mechanisms, spectroscopy, organic synthesis, and some molecules of nature.

Course Homepage: [[http://oyc.yale.edu/chemistry/chem-125b]]

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Uploaded videos:

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01:37:59

Lecture 1 - Mechanism: How Energies and Kinetic Order Influence Reaction Rates

J. Michael McBride

Aug 19, 2014

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3030 Views

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48:13

Lecture 2 - Peculiar Rate Laws, Bond Dissociation Energies, and Relative Reactiv...

J. Michael McBride

Aug 19, 2014

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1696 Views

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46:07

Lecture 3 - Rate and Selectivity in Radical-Chain Reactions

J. Michael McBride

Aug 19, 2014

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1614 Views

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Lecture 4 - Electronegativity, Bond Strength, Electrostatics, and Non-Bonded Int...

J. Michael McBride

Aug 19, 2014

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1677 Views

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47:09

Lecture 5 - Solvation, H-Bonding, and Ionophores

J. Michael McBride

Aug 19, 2014

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1635 Views

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46:46

Lecture 6 - Brønsted Acidity and the Generality of Nucleophilic Substitution

J. Michael McBride

Aug 19, 2014

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1649 Views

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Lecture 7 - Nucleophilic Substitution Tools - Stereochemistry, Rate Law, Substra...

J. Michael McBride

Aug 19, 2014

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1734 Views

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Lecture 8 - Solvent, Leaving Group, Bridgehead Substitution, and Pentavalent Car...

J. Michael McBride

Aug 19, 2014

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1395 Views

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Lecture 9 - Pentavalent Carbon? E2, SN1, E1

J. Michael McBride

Aug 19, 2014

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1518 Views

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Lecture 10 - Cation Intermediates – Alkenes: Formation, Addition, and Stability

J. Michael McBride

Aug 19, 2014

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1462 Views

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Lecture 11 - Carbocations and the Mechanism of Electrophilic Addition to Alkenes...

J. Michael McBride

Aug 19, 2014

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1592 Views

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Lecture 12 - Nucleophilic Participation During Electrophilic Addition to Alkenes...

J. Michael McBride

Aug 19, 2014

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1596 Views

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Lecture 13 - Addition to Form Three-Membered Rings: Carbenoids and Epoxidation

J. Michael McBride

Aug 19, 2014

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1648 Views

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Lecture 14 - Epoxide Opening, Dipolar Cycloaddition, and Ozonolysis

J. Michael McBride

Aug 19, 2014

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1608 Views

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Lecture 15 - Metals and Catalysis in Alkene Oxidation, Hydrogenation, Metathesis...

J. Michael McBride

Aug 19, 2014

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2008 Views

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Lecture 16 - Isoprenoids, Rubber, and Tuning Polymer Properties

J. Michael McBride

Aug 19, 2014

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Lecture 17 - Alkynes; Conjugation in Allylic Intermediates and Dienes

J. Michael McBride

Aug 19, 2014

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Lecture 18 - Linear and Cyclic Conjugation Theory; 4n+2 Aromaticity

J. Michael McBride

Aug 19, 2014

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Lecture 19 - Aromatic Transition States: Cycloaddition and Electrocyclic Reactio...

J. Michael McBride

Aug 19, 2014

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1947 Views

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Lecture 21 - Functional Groups and Fingerprints in IR Spectroscopy; Precession o...

J. Michael McBride

Aug 19, 2014

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1887 Views

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Lecture 20 - Electronic and Vibrational Spectroscopy

J. Michael McBride

Aug 19, 2014

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1590 Views

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Lecture 22 - Medical MRI and Chemical NMR

J. Michael McBride

Aug 19, 2014

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1958 Views

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Lecture 23 - Diamagnetic Anisotropy and Spin-Spin Splitting

J. Michael McBride

Aug 19, 2014

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1469 Views

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Lecture 24 - Higher-Order Effects, Dynamics, and the NMR Time Scale

J. Michael McBride

Aug 19, 2014

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1562 Views

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Lecture 25 - C-13 and 2D NMR – Electrophilic Aromatic Substitution

J. Michael McBride

Aug 19, 2014

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1528 Views

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50:48

Lecture 26 - Aromatic Substitution in Synthesis: Friedel-Crafts and Moses Gomber...

J. Michael McBride

Aug 19, 2014

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1516 Views

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45:33

Lecture 27 - Triphenylmethyl and an Introduction to Carbonyl Chemistry

J. Michael McBride

Aug 19, 2014

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1571 Views

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Lecture 28 - Mechanism and Equilibrium of Carbonyl Reactions

J. Michael McBride

Aug 19, 2014

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1463 Views

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Lecture 29 - Imines and Enamines; Oxidation and Reduction

J. Michael McBride

Aug 19, 2014

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1750 Views

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Lecture 30 - Oxidation States and Mechanisms

J. Michael McBride

Aug 19, 2014

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1631 Views

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Lecture 32 - Measuring Bond Energies: Guest Lecture by Prof. G. Barney Ellison

J. Michael McBride

Aug 19, 2014

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1217 Views

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Lecture 31 - Periodate Cleavage, Retrosynthesis, and Green Chemistry

J. Michael McBride

Aug 19, 2014

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1275 Views

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Lecture 33 - Green Chemistry; Acids and Acid Derivatives

J. Michael McBride

Aug 19, 2014

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Lecture 34 - Acids and Acid Derivatives

J. Michael McBride

Aug 19, 2014

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1419 Views

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Lecture 35 - Acyl Insertions and α-Reactivity

J. Michael McBride

Aug 19, 2014

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1404 Views

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Lecture 36 - α-Reactivity and Condensation Reactions

J. Michael McBride

Aug 19, 2014

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1554 Views

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Lecture 37 - Proving the Configuration of Glucose and Synthesizing Two Unnatural...

J. Michael McBride

Aug 19, 2014

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1530 Views

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Lecture 38 - Review: Synthesis of Cortisone

J. Michael McBride

Aug 19, 2014

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1413 Views

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