About
In making advances within Computational Systems Biology there is an acknowledged need for the ongoing development of both probabilistic and mechanistic, possibly multi-scale, models of complex biological processes. In addition to such models the development of appropriate and efficient inferential methodology to identify and reason over such models is necessary.
Examples of the progress which has been made in our understanding of modern biology by the exploitation of such methodology include model based inference of p53 activity; uncovering the evolution of protein complexes and understanding the circadian clock in plants; details of which were presented at the LICSB workshops.
The previous workshop themes of parameter estimation, probabilistic modelling of networks and inference in large biological system models will be further explored in this meeting.
Find out more at the Workshop website.
Videos

Beyond Molecular Biology – Applying Gene Regulation Network Inference Methods in...
Apr 16, 2009
·
3957 views

Inference in a probabilistic model of dynamic DNA
Apr 16, 2009
·
3312 views

Exploring experimental designs for network inference using perturbations and a B...
Apr 16, 2009
·
3097 views

Role of Gene Mutations Predicted from a Computational Model of the Cochlea of th...
Apr 16, 2009
·
3172 views

Moment closure and block updating for parameter inference in stochastic biologic...
Apr 16, 2009
·
2928 views

Bayesian model selection: mechanistic models of Erk MAP kinase phosphorylation d...
Apr 16, 2009
·
6003 views

Temporal Development and Collapse of an Arctic Plant-Pollinator Network
Apr 16, 2009
·
2968 views

Definition of Valid Proteomic Biomarkers: Bayesian Solutions to a Currently Unme...
Apr 16, 2009
·
4054 views

Detecting Evolutionary Inter-Gene Heterogeneity in Borrelia burgdorferi
Apr 16, 2009
·
5002 views

Bayesian Hypotheses Testing in Raman Spectroscopy
Apr 16, 2009
·
4748 views

Estimation of Multiple Transcription Factor Activities using ODEs and Gaussian P...
Apr 16, 2009
·
4898 views

Genotyping Structural Variation
Apr 16, 2009
·
2738 views

Gaussian process regression bootstrapping
Apr 16, 2009
·
5778 views

Time-varying genetic network inference using informative priors
Apr 16, 2009
·
4669 views

Hybrid Inference for Stochastic Kinetic Models
Apr 16, 2009
·
3132 views

Opening - LICSB '09
Apr 16, 2009
·
2830 views