About
In making advances within Computational Systems Biology there is an acknowledged need for the ongoing development of both probabilistic and mechanistic, possibly multi-scale, models of complex biological processes. In addition to such models the development of appropriate and efficient inferential methodology to identify and reason over such models is necessary.
Examples of the progress which has been made in our understanding of modern biology by the exploitation of such methodology include model based inference of p53 activity; uncovering the evolution of protein complexes and understanding the circadian clock in plants; details of which were presented at the LICSB workshops.
The previous workshop themes of parameter estimation, probabilistic modelling of networks and inference in large biological system models will be further explored in this meeting.
Find out more at the Workshop website.
Videos

Estimation of Multiple Transcription Factor Activities using ODEs and Gaussian P...
Apr 16, 2009
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4889 views

Role of Gene Mutations Predicted from a Computational Model of the Cochlea of th...
Apr 16, 2009
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3159 views

Detecting Evolutionary Inter-Gene Heterogeneity in Borrelia burgdorferi
Apr 16, 2009
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4998 views

Beyond Molecular Biology – Applying Gene Regulation Network Inference Methods in...
Apr 16, 2009
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3944 views

Temporal Development and Collapse of an Arctic Plant-Pollinator Network
Apr 16, 2009
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2960 views

Genotyping Structural Variation
Apr 16, 2009
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2732 views

Opening - LICSB '09
Apr 16, 2009
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2823 views

Bayesian model selection: mechanistic models of Erk MAP kinase phosphorylation d...
Apr 16, 2009
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5997 views

Hybrid Inference for Stochastic Kinetic Models
Apr 16, 2009
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3129 views

Bayesian Hypotheses Testing in Raman Spectroscopy
Apr 16, 2009
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4736 views

Exploring experimental designs for network inference using perturbations and a B...
Apr 16, 2009
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3092 views

Gaussian process regression bootstrapping
Apr 16, 2009
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5773 views

Time-varying genetic network inference using informative priors
Apr 16, 2009
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4661 views

Moment closure and block updating for parameter inference in stochastic biologic...
Apr 16, 2009
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2921 views

Inference in a probabilistic model of dynamic DNA
Apr 16, 2009
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3304 views

Definition of Valid Proteomic Biomarkers: Bayesian Solutions to a Currently Unme...
Apr 16, 2009
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4049 views