A Robust Spelling Device for Locked-In Patients Based on Real-Time fMRI

author: Rainer Goebel, Faculty of Psychology, Maastricht University
published: Aug. 10, 2009,   recorded: July 2009,   views: 5538


Related Open Educational Resources

Related content

Report a problem or upload files

If you have found a problem with this lecture or would like to send us extra material, articles, exercises, etc., please use our ticket system to describe your request and upload the data.
Enter your e-mail into the 'Cc' field, and we will keep you updated with your request's status.
Lecture popularity: You need to login to cast your vote.


Several medical conditions (e.g., brain injury, stroke, progressive neurological diseases) can lead to complete paralysis while largely preserving sensory and cognitive functions and associated brain activation. We investigated whether healthy subjects are able to "write" solely on the basis of voluntary control of the fMRI (BOLD) signal. Using a guided display technique, we show that subjects can learn in less than half an hour to produce reliably any letter of the alphabet in a single trial. To achieve this performance, subjects use three mental strategies to modulate spatio-temporal properties of the fMRI signal in three different brain areas. While the transmitted information (BOLD time courses from regions-of-interest) has been initially decoded offline by human raters, we have recently implemented a fully automatized real-time "brain reading" technique.The developed paradigm and decoding technique might be applied in locked-in patients to let them communicate their wishes and thoughts reliably without extensive pre-training.

See Also:

Download slides icon Download slides: bbci09_goebel_arsd_01.pdf (12.2┬áMB)

Help icon Streaming Video Help

Link this page

Would you like to put a link to this lecture on your homepage?
Go ahead! Copy the HTML snippet !

Write your own review or comment:

make sure you have javascript enabled or clear this field: