CHEM 125 - Freshman Organic Chemistry

CHEM 125 - Freshman Organic Chemistry

37 Lectures ยท Sep 30, 2008

About

This is the first semester in a two-semester introductory course focused on current theories of structure and mechanism in organic chemistry, their historical development, and their basis in experimental observation. The course is open to freshmen with excellent preparation in chemistry and physics, and it aims to develop both taste for original science and intellectual skills necessary for creative research.

Course Homepage: [[http://oyc.yale.edu/chemistry/freshman-organic-chemistry/]]

Course features at Open Yale courses page: *Freshman Organic Chemistry *Syllabus *Class Sessions *Downloads *Survey

Exams: *Midterm Exam 1 *Midterm Exam 2 *Midterm Exam 3 *Final Exam

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Lecture 1 - How Do You Know? Freshman Organic Chemistry

J. Michael McBride

Jun 09, 2010

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Lecture 2 - Force Laws, Lewis Structures and Resonance

J. Michael McBride

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Lecture 3 - Double Minima, Earnshaw's Theorem and Plum-Puddings

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Lecture 4 - Coping with Smallness and Scanning Probe Microscopy

J. Michael McBride

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Lecture 5 - X-Ray Diffraction

J. Michael McBride

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Lecture 6 - Seeing Bonds by Electron Difference Density

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Lecture 7 - Quantum Mechanical Kinetic Energy

J. Michael McBride

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Lecture 8 - One-Dimensional Wave Functions

J. Michael McBride

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Lecture 9 - Chladni Figures and One-Electron Atoms

J. Michael McBride

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Lecture 10 - Reality and the Orbital Approximation

J. Michael McBride

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Lecture 11 - Orbital Correction and Plum-Pudding Molecules

J. Michael McBride

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Lecture 12 - Overlap and Atom-Pair Bonds

J. Michael McBride

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Lecture 13 - Overlap and Energy-Match

J. Michael McBride

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Lecture 14 - Checking Hybridization Theory with XH3

J. Michael McBride

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Lecture 15 - Chemical Reactivity: SOMO, HOMO, and LUMO

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Lecture 16 - Recognizing Functional Groups

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Lecture 17 - Reaction Analogies and Carbonyl Reactivity

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Lecture 18 - Amide, Carboxylic Acid and Alkyl Lithium

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Lecture 19 - Oxygen and the Chemical Revolution (Beginning to 1789)

J. Michael McBride

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Lecture 20 - Rise of the Atomic Theory (1790-1805)

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Lecture 21 - Berzelius to Liebig and Wรถhler (1805-1832)

J. Michael McBride

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Lecture 22 - Radical and Type Theories (1832-1850)

J. Michael McBride

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Lecture 23 - Valence Theory and Constitutional Structure (1858)

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Lecture 24 - Determining Chemical Structure by Isomer Counting (1869)

J. Michael McBride

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Lecture 25 - Models in 3D Space (1869-1877); Optical Isomers

J. Michael McBride

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Lecture 26 - Van't Hoff's Tetrahedral Carbon and Chirality

J. Michael McBride

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Lecture 27 - Communicating Molecular Structure in Diagrams and Words

J. Michael McBride

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Lecture 28 - Stereochemical Nomenclature; Racemization and Resolution

J. Michael McBride

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Lecture 29 - Preparing Single Enantiomers and the Mechanism of Optical Rotation

J. Michael McBride

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Lecture 30 - Esomeprazole as an Example of Drug Testing and Usage

J. Michael McBride

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Lecture 31 - Preparing Single Enantiomers and Conformational Energy

J. Michael McBride

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Lecture 32 - Stereotopicity and Baeyer Strain Theory

J. Michael McBride

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Lecture 33 - Conformational Energy and Molecular Mechanics

J. Michael McBride

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Lecture 34 - Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes

J. Michael McBride

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Lecture 35 - Understanding Molecular Structure and Energy through Standard Bonds

J. Michael McBride

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Lecture 36 - Bond Energies, the Boltzmann Factor and Entropy

J. Michael McBride

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Lecture 37 - Potential Energy Surfaces, Transition State Theory and Reaction Me...

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