Iterated Local Search for Biclustering of Microarray Data

author: Wassim Ayadi, Computer Science Department, Universite Angers
published: Oct. 14, 2010,   recorded: September 2010,   views: 3356
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Description

In the context of microarray data analysis, biclustering aims to identify simultaneously a group of genes that are highly correlated across a group of experimental conditions. This paper presents a Biclustering Iterative Local Search (BILS) algorithm to the problem of biclustering of microarray data. The proposed algorithm is highlighted by the use of some original features including a new evaluation function, a dedicated neighborhood relation and a tailored perturbation strategy. The BILS algorithm is assessed on the well-known yeast cell-cycle dataset and compared with two most popular algorithms.

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