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Sparse Linear Models Explain Phenotypic Variation and Predict Risk of Complex Disease
Published on Jan 23, 20123941 Views
A central goal of medical genetics is to create models that accurately predict complex disease given genotype. To maximize predictive value and identify causal single-nucleotide polymorphisms (SNPs)
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Chapter list
Sparse Linear Models Explain Phenotypic Variation and Predict Risk of Complex Disease00:00
The Genetic Basis of Complex Disease00:11
Methods00:50
Results - Celiac Disease Cross-Validation01:28
Results - Celiac Disease External Validation03:14
Conclusions03:22