Biološke nanopore

author: Gregor Anderluh, Laboratorij za molekularno biologijo in nanobiotehnologijo, Kemijski inštitut Ljubljana
published: Feb. 12, 2013,   recorded: January 2013,   views: 4087
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Description

Celične lipidne membrane so ključne za normalno delovanje organizmov. Omogočajo selektivno prepuščanje snovi in varujejo notranjost celice pred vplivi iz okolja. Patogeni organizmi so razvili mnogo mehanizmov, ki privedejo do poškodb celičnih membran ali spremembe njihove zgradbe in jim tako omogočijo vstop v celice. Pri enem od teh mehanizmov peptidi in proteini poškodujejo lipidne membrane s tvorbo por nanometrskih dimenzij. Tako lahko delujejo nekateri naravni toksini kot tudi proteini, ki sodelujejo v imunskem odzivu v procesu uničevanja tarčnih celic. V predavanju bodo predstavljene nekatere značilnosti proteinskih nanopor in možni načini uporabe v biomedicini in nanobiotehnologiji.

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Download slides icon Download slides: kolokviji_anderluh_nanopore_01.pdf (6.2 MB)


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