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4th European Phd Complexity School

Emergence of complexity in biological networks: from selection to tinkering

author: Ricard V. Solé, Pompeu Fabra University

Description

Recent work has been searching for general principles of organization and evolution of natural and artificial systems changing through local rules based on reuse of previously existing substructures. Such a process of "tinkering" makes a big difference (at least in principle) when comparing biological structures and man-made artifacts. As pointed out by the French biologist François Jacob, the engineer is able to foresee the future use of the artifact (i.e. it acts as a designer) whereas evolution does not. The first can ignore previous designs, whereas the second is based on changes taking place by using available structures. In spite of its apparent drawbacks, tinkering has been able to generate most complex structures observable in the real world (including some in the technological world). Very often, the resulting structures share common principles of organization, suggesting that convergent evolution towards a limited number of basic plans is inevitable. How innovations emerge through evolution is one of the key problems in complexity. Recent work on evolved complex networks suggests that tinkering is a main driving force shaping complex systems and that several desirable properties, including modularity, might emerge for free under tinkered evolution.

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Slides
0:00 EMERGENCE OF COMPLEXITY IN BIOLOGICAL NETWORKS
1:46 Evolution in physics?
2:25 Evolution: how does it take place?
6:12 Does evolution occur at all?
7:10 Can life be created in the lab?
7:15 Evolution of complexity: networks
7:37 Complex networks are scale-free
8:15 Cell Biology
9:26 The small world of protein interactions
10:02 Scale-free genome architecture
10:53 Proteome: small world, scale free
11:17 Evolution of genome : how to model?
12:11 Complexity “for free”?
12:56 Origins of scale-free regulatory maps part1
14:25 Origins of scale-free regulatory maps part2
14:45 Structure emerges without functionality
15:35 Modular networks
16:44 Cellular networks are modular
17:16 Modularity for free?
17:36 Language
21:25 Language universals
23:59 Network of word co-occurrences part1
24:27 Network of word co-occurrences part2
25:02 The small world of human language
27:13 The ontogeny of human language
31:13 Language acquisition: the innate element
36:34 Complex Systems Lab

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