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Like a hurricane: a journey with Tamara into the glioma stem cell niche
Published on Dec 09, 2017834 Views
Tamara and I work together for more than 25 years. The role of proteases in health and disease was our first joint interest and that is still the case today. However, the role of proteases has been na
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Chapter list
Like a hurricane: A journey with Tamara into the glioma stem cell niche00:00
First encounter of Tamara and Ron02:01
Second and following encounters03:07
Cathepsin B in normal colon, polyp and colon cancer03:47
Colon cancer metastasis in liver05:21
Cathepsin B at the plasma membrane of colon cancer cells06:26
Our first major joint achievement06:41
The cancer degradome and the tumor microenvironment08:23
Our mutual interest extended to glioblastoma09:16
Cathepsin K in glioblastoma11:07
Glioma stem cell niche11:35
Histology of artery and vein12:13
Glioma stem cell niche around arteriolar adventita13:02
Glioma stem cell niche: chemoattractive receptors and ligands in adventita13:26
Cathepsin B, K and X in glioma stem cell niches 13:51
Cathepsin B, L and X in glioma stem cell niches14:08
Histology of artery and vein14:25
The glioma stem cell niche is a copy of the hematopoietic stem cell niche in bone marrow 14:54
A journey into the glioma stem cell niches with hurricane Tamara15:23